Opportunity Information: Apply for TI 21 006
The Medication Assisted Treatment - Prescription Drug and Opioid Addiction (MAT-PDOA) grant (Funding Opportunity Number TI 21 006) is a discretionary federal grant program run by the U.S. Department of Health and Human Services through the Substance Abuse and Mental Health Services Administration (SAMHSA), specifically its Center for Substance Abuse Treatment (CSAT). It was announced for fiscal year 2021 and is tied to CFDA/Assistance Listing 93.243, placing it within SAMHSA's health-focused portfolio of substance use prevention and treatment funding.
The central goal of MAT-PDOA is to expand and strengthen access to medication-assisted treatment (MAT) for people with opioid use disorder (OUD), including individuals who are actively seeking MAT as well as those already enrolled and needing improved continuity or quality of services. In practice, this means the program is aimed at increasing treatment capacity and improving the ability of providers and systems of care to deliver evidence-based medications for OUD (such as buprenorphine, methadone, and naltrexone) alongside the clinical and recovery supports that help patients start treatment, remain engaged, and reduce relapse risk. The emphasis is not just on offering medication, but on reducing barriers to receiving it and improving the overall delivery of MAT services so that more people can access care in a timely, sustained way.
SAMHSA outlines two primary outcome targets for grantees. First, the program seeks an increase in the number of individuals with OUD who receive MAT, reflecting a direct push to close treatment gaps and reach more people with proven interventions. Second, the program seeks measurable reductions in illicit opioid use and prescription opioid misuse, assessed at a six-month follow-up point, which signals that applicants are expected to track patient outcomes over time rather than only reporting short-term service counts. Together, these outcomes show that the program prioritizes both expanded reach (more people served) and real-world impact (less misuse and illicit use after treatment engagement).
From a funding and competition standpoint, MAT-PDOA offered an award ceiling of $1,000,000 per award, with SAMHSA expecting to make approximately 135 awards. The opportunity was posted on February 26, 2021, and the original application deadline was April 27, 2021. The funding instrument is a grant, and the activity category is health, reflecting the program's role in supporting treatment delivery infrastructure and patient care services rather than, for example, purely research or capital construction.
Eligibility is listed broadly as "Others," with the note that applicants should consult SAMHSA's additional eligibility language in the full announcement for specific qualifications and restrictions. That phrasing typically indicates eligibility may include a range of organization types beyond only state governments, potentially covering certain treatment providers, community-based organizations, and other entities that meet SAMHSA requirements. In short, MAT-PDOA is designed to help communities scale effective opioid treatment by expanding access to MAT and demonstrating improved patient outcomes within a defined follow-up period.Apply for TI 21 006
- The Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis in the health sector is offering a public funding opportunity titled "Medication Assisted Treatment - Prescription Drug and Opioid Addiction" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.243.
- This funding opportunity was created on Feb 26, 2021.
- Applicants must submit their applications by Apr 27, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 135 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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MAT-PDOA Grant (TI 21 006) FAQs
What is the MAT-PDOA grant?
The Medication Assisted Treatment - Prescription Drug and Opioid Addiction (MAT-PDOA) grant is a discretionary federal grant program that supports efforts to expand and strengthen access to medication-assisted treatment (MAT) for people with opioid use disorder (OUD).
What is the Funding Opportunity Number (FON) for this program?
The Funding Opportunity Number is TI 21 006.
Which federal agency runs this grant program?
This program is run by the U.S. Department of Health and Human Services (HHS) through the Substance Abuse and Mental Health Services Administration (SAMHSA).
Which SAMHSA center is associated with MAT-PDOA?
The grant is associated with SAMHSA's Center for Substance Abuse Treatment (CSAT).
What fiscal year was this opportunity announced for?
This opportunity was announced for fiscal year 2021.
What is the CFDA/Assistance Listing number for MAT-PDOA?
The CFDA/Assistance Listing number is 93.243.
What is the main purpose of the MAT-PDOA grant?
The main purpose is to expand and strengthen access to medication-assisted treatment (MAT) for individuals with opioid use disorder, including people actively seeking MAT and people already enrolled who need improved continuity or quality of services.
Who is this program intended to serve?
The program is intended to serve individuals with opioid use disorder (OUD), including those trying to start MAT and those already receiving MAT who may benefit from better continuity of care or improved service quality.
What does SAMHSA mean by "expanding access" to MAT in this program?
In this program, expanding access means increasing treatment capacity and improving the ability of providers and systems of care to deliver evidence-based medications for OUD along with supports that help patients start treatment, remain engaged, and reduce relapse risk. It also emphasizes reducing barriers so more people can receive MAT in a timely and sustained way.
Does the program focus only on medication, or also on services that support treatment?
The emphasis is not only on offering medication. The program also stresses improving the overall delivery of MAT services and reducing barriers to receiving care, alongside clinical and recovery supports that help patients begin and stay engaged in treatment.
What medications are referenced as examples of evidence-based MAT for OUD?
The opportunity references evidence-based medications for OUD such as buprenorphine, methadone, and naltrexone.
What outcome targets does SAMHSA highlight for grantees?
SAMHSA highlights two primary outcome targets: (1) an increase in the number of individuals with OUD who receive MAT, and (2) measurable reductions in illicit opioid use and prescription opioid misuse at a six-month follow-up point.
Is there an expectation to track outcomes over time?
Yes. The opportunity indicates that reductions in illicit opioid use and prescription opioid misuse are assessed at a six-month follow-up, which implies applicants are expected to track outcomes beyond short-term service counts.
What is the maximum award amount (award ceiling) for MAT-PDOA?
The award ceiling listed is $1,000,000 per award.
Approximately how many awards did SAMHSA expect to make?
SAMHSA expected to make approximately 135 awards.
When was the opportunity posted?
The opportunity was posted on February 26, 2021.
What was the original application deadline?
The original application deadline was April 27, 2021.
What type of funding instrument is used for MAT-PDOA?
The funding instrument is a grant.
What is the activity category for this opportunity?
The activity category is health.
Is this program focused on research or on service delivery?
Based on the description provided, the program supports treatment delivery infrastructure and patient care services aimed at expanding access to MAT and improving outcomes, rather than being described as a purely research-focused opportunity.
Who is eligible to apply?
Eligibility is listed broadly as "Others." The description notes that applicants should consult SAMHSA's additional eligibility language in the full announcement for specific qualifications and restrictions.
What does it mean that eligibility is listed as "Others"?
It means the eligible applicant types are not limited to a single category in the summary and may include a range of organizations beyond only state governments. The summary suggests this could potentially cover certain treatment providers, community-based organizations, and other entities that meet SAMHSA requirements, but the definitive rules are in the full announcement.
What kinds of improvements is MAT-PDOA trying to achieve in systems of care?
The program is aimed at increasing treatment capacity, improving continuity and quality of MAT services, reducing barriers to receiving MAT, and strengthening the supports that help people initiate treatment, stay engaged, and reduce relapse risk.
How does MAT-PDOA define success at the client level?
The provided description indicates success includes more individuals with OUD receiving MAT and measurable reductions in illicit opioid use and prescription opioid misuse at six-month follow-up.
What problem is this grant designed to address?
It is designed to close treatment gaps for opioid use disorder by scaling access to evidence-based medication treatment and improving the delivery of services so people can start and continue MAT and achieve reductions in misuse and illicit opioid use.
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