Opportunity Information: Apply for RFA DK 15 028

The National Institutes of Health (NIH) funding opportunity titled "Impact of the Use of Glucose Monitoring and Control Technologies on Health Outcomes and Quality of Life in Older Adults with Type 1 Diabetes (T1D) (DP3)" (Funding Opportunity Number RFA DK 15 028; CFDA 93.847) supports clinical studies that evaluate how current and emerging diabetes technologies perform specifically in older adults living with type 1 diabetes. The central idea is that tools such as advanced blood glucose monitoring systems and insulin delivery approaches may offer meaningful benefits, but the real-world balance of risks and advantages could look different in older patients than it does in younger populations that are often the focus of technology trials. NIH is therefore encouraging research that directly tests these technologies in older adults, with an emphasis on measurable health outcomes, glucose management, and day-to-day quality of life.

A key motivation for the program is that older adults with type 1 diabetes can be more vulnerable to serious hypoglycemia and may also face cognitive impairment, functional limitations, or multiple co-existing medical conditions. These factors can influence whether a technology is safe, usable, and beneficial. For example, a device that improves time-in-range in a younger adult might create new challenges for an older person who has visual impairment, reduced manual dexterity, difficulty interpreting alarms, or limited caregiver support. Likewise, co-morbidities and polypharmacy can change hypoglycemia risk or complicate self-management routines. The FOA is aimed at generating evidence that accounts for these age-related and clinical complexities rather than assuming that outcomes will generalize across age groups.

The clinical studies encouraged under this announcement are intended to determine whether technologies for glucose monitoring and insulin administration lead to improvements in outcomes that matter to older adults, including better glucose control and fewer adverse events, while also addressing patient-centered outcomes such as independence, treatment burden, confidence in self-management, and overall quality of life. Although the announcement description is broad, it clearly frames the research around practical, health-impacting questions: how well these technologies work in older people with T1D, what risks they introduce or reduce (especially around hypoglycemia), and how they affect everyday living in a population that may have distinct needs and constraints.

This is a discretionary grant opportunity within the NIH mission areas related to health and nutrition. A wide range of organizations are eligible to apply. Eligible applicants include various levels of government (state, county, city/township, and special district governments), public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, and public or Indian housing authorities. The eligibility list also includes federally recognized Native American tribal governments and other Native American tribal organizations, nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in those categories), for-profit organizations other than small businesses, and small businesses. In addition, the announcement explicitly highlights eligibility for a number of institution types and organizations that are often emphasized in federal research programs, including Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations). This breadth signals an intent to encourage diverse research settings and populations, including studies that may be embedded in community, tribal, or regionally focused healthcare environments.

Administrative details in the source indicate the FOA was created on September 24, 2015, with an original closing date of March 3, 2016. The funding instrument type is a grant, and it is categorized under discretionary funding. The provided source excerpt does not specify an award ceiling or the expected number of awards, suggesting those details either were not included in the excerpted fields or may have been defined elsewhere in the full announcement.

Overall, this opportunity is focused on producing clinically meaningful, age-relevant evidence about diabetes technology use in older adults with type 1 diabetes, with explicit attention to safety concerns like hypoglycemia and real-life challenges such as cognitive impairment and multiple co-morbidities. The intended end result is clearer guidance on which monitoring and insulin-delivery technologies improve health outcomes and quality of life for older patients, and under what conditions they are most effective and safest.

  • The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Impact of the Use of Glucose Monitoring and Control Technologies on Health Outcomes and Quality of Life in Older Adults with Type 1 Diabetes (T1D) (DP3)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
  • This funding opportunity was created on 2015-09-24.
  • Applicants must submit their applications by 2016-03-03. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)

What is the title of this NIH funding opportunity?

The funding opportunity is titled "Impact of the Use of Glucose Monitoring and Control Technologies on Health Outcomes and Quality of Life in Older Adults with Type 1 Diabetes (T1D) (DP3)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA DK 15 028.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.847.

What type of funding instrument is used for this opportunity?

The funding instrument type is a grant.

Is this a discretionary or mandatory funding opportunity?

This is a discretionary grant opportunity.

What kinds of studies does this FOA support?

This FOA supports clinical studies that evaluate how current and emerging diabetes technologies perform specifically in older adults living with type 1 diabetes.

What is the main purpose of the research encouraged by this program?

The program is intended to generate evidence on how glucose monitoring and insulin administration technologies affect health outcomes and quality of life in older adults with type 1 diabetes, recognizing that risks and benefits may differ from those seen in younger populations.

What types of diabetes technologies are the focus of the FOA?

The FOA focuses on technologies for glucose monitoring and insulin delivery, including advanced blood glucose monitoring systems and insulin delivery approaches.

Why does NIH emphasize studying these technologies in older adults rather than relying on evidence from younger populations?

The FOA highlights that older adults with type 1 diabetes may have different vulnerabilities and real-world constraints (for example, higher hypoglycemia risk, cognitive impairment, functional limitations, and multiple co-existing medical conditions). These factors can affect safety, usability, and overall benefit in ways that may not be captured in studies centered on younger people.

What health risks in older adults with type 1 diabetes are specifically mentioned as a motivation for this research?

The FOA specifically notes vulnerability to serious hypoglycemia, and also points to cognitive impairment, functional limitations, and multiple co-existing medical conditions as factors that may influence technology performance and safety.

What usability or day-to-day challenges for older adults are mentioned in the description?

The description mentions that issues such as visual impairment, reduced manual dexterity, difficulty interpreting alarms, and limited caregiver support can create challenges for older adults using diabetes technologies.

How do co-morbidities and polypharmacy relate to the goals of this FOA?

The FOA notes that co-morbidities and polypharmacy can change hypoglycemia risk and complicate self-management routines, which is part of why technologies must be evaluated in older adults under real-world, age-related complexities.

What outcomes are these clinical studies expected to measure?

The FOA emphasizes measurable health outcomes, glucose management, and adverse events (especially hypoglycemia), along with patient-centered outcomes that matter to older adults.

What patient-centered outcomes are specifically highlighted?

The FOA highlights outcomes such as independence, treatment burden, confidence in self-management, and overall quality of life.

Does the FOA focus only on glucose control metrics?

No. While glucose control and safety outcomes are central, the FOA also emphasizes day-to-day quality of life and other patient-centered outcomes relevant to older adults.

What is the overarching question this FOA is trying to answer?

The FOA is centered on practical, health-impacting questions: how well glucose monitoring and insulin-delivery technologies work in older adults with type 1 diabetes, what risks they introduce or reduce (particularly around hypoglycemia), and how they affect everyday living for a population with distinct needs and constraints.

When was this FOA created?

The administrative details provided state that the FOA was created on September 24, 2015.

What was the original closing date listed for this opportunity?

The original closing date listed is March 3, 2016.

Who is eligible to apply?

A wide range of organizations are eligible, including various levels of government, public and private institutions of higher education, independent school districts, public or Indian housing authorities, federally recognized tribal governments and other tribal organizations, nonprofits (with or without 501(c)(3) status, as specified), for-profit organizations other than small businesses, and small businesses.

Are state, county, city, township, or special district governments eligible applicants?

Yes. The eligibility list includes state governments, county governments, city or township governments, and special district governments.

Are colleges and universities eligible?

Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.

Are independent school districts eligible?

Yes. Independent school districts are included in the eligibility list.

Are public or Indian housing authorities eligible to apply?

Yes. Public and Indian housing authorities are included as eligible applicants.

Are tribal governments and tribal organizations eligible?

Yes. Federally recognized Native American tribal governments and other Native American tribal organizations are eligible.

Are nonprofits eligible, and does 501(c)(3) status matter?

Yes. Nonprofits with or without 501(c)(3) status are listed as eligible, with the caveat in the provided description that these nonprofit categories are eligible as long as they are not institutions of higher education in those categories.

Are for-profit organizations eligible?

Yes. The eligibility list includes for-profit organizations other than small businesses, and it also separately lists small businesses as eligible.

Are small businesses eligible to apply?

Yes. Small businesses are included in the eligibility list.

Does the FOA highlight participation from specific institution types such as HBCUs or Hispanic-serving institutions?

Yes. The announcement explicitly highlights eligibility for institution types and organizations often emphasized in federal research programs, including HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and other serving institution categories.

Are faith-based or community-based organizations eligible?

Yes. The announcement explicitly includes faith-based or community-based organizations in the highlighted eligibility list.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are explicitly included in the highlighted eligibility list.

Are non-U.S. entities (foreign organizations) eligible to apply?

Yes. The eligibility list explicitly includes non-U.S. entities (foreign organizations).

Does the provided information list an award ceiling or the expected number of awards?

No. The provided source excerpt does not specify an award ceiling or the expected number of awards, indicating those details were not included in the excerpted fields or may exist elsewhere in the full announcement.

What is the expected impact of research funded under this opportunity?

The stated intent is to produce clinically meaningful, age-relevant evidence about diabetes technology use in older adults with type 1 diabetes, with attention to safety (especially hypoglycemia) and real-life challenges, ultimately supporting clearer guidance on which technologies improve health outcomes and quality of life and under what conditions they are most effective and safest.

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