Opportunity Information: Apply for PA 21 202
The AHRQ/PCORI Learning Health System Small Grant Pilot Program (Funding Opportunity Number PA 21 202) is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ), developed in partnership with the Patient-Centered Outcomes Research Institute (PCORI). It funds small, innovative pilot projects focused on patient-centered outcomes research conducted within Learning Health Systems (LHS). The central idea is to support research that is embedded in real-world care settings and operational workflows, so the work is closely tied to decisions health systems are already making and to outcomes that matter to patients, clinicians, and other stakeholders.
This program is specifically aimed at two connected goals. First, it supports pilots that evaluate the outcomes of embedded research itself, meaning applicants should look at what changes or benefits occur when research is built into the health system environment (for example, improvements in patient outcomes, care processes, service delivery, quality measures, equity, or other priorities the health system identifies). Second, it encourages applicants to study the processes that make embedded research effective, such as how the research team partners with health system leaders, how patients and other stakeholders are engaged, how findings are implemented, and what practical factors help or hinder the impact of the research. In other words, the program is not only interested in whether an intervention or approach works, but also in how the embedded research model can strengthen impact, stakeholder engagement, and learning within the system.
Eligible applicants cover a wide range of U.S.-based organizations and government entities consistent with the program’s health-focused mission (CFDA 93.226). Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); Native American tribal organizations (other than federally recognized tribal governments); public housing authorities and Indian housing authorities; and nonprofits both with and without 501(c)(3) status (as long as they are not institutions of higher education in the nonprofit category). The opportunity also notes additional eligible groups such as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and several categories of minority-serving institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions, as well as Asian American Native American Pacific Islander Serving Institutions (AANAPISISs). It also lists eligible agencies of the federal government among the applicant types.
At the same time, there are clear restrictions on foreign participation. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are not eligible to apply. So while the program is broad within the U.S. ecosystem, it is designed to be carried out domestically and within U.S.-based organizational structures.
From an administrative standpoint, this is a grant (Funding Instrument Type: Grant) in the health activity category. The posting was created on 2021-03-11, and the original closing date listed is 2023-06-19. The summary information provided does not specify an award ceiling or the expected number of awards, which means applicants typically need to consult the full announcement to understand anticipated budget ranges, project period, and the scale of awards.
Overall, this pilot program is best understood as support for practical, real-world, patient-centered outcomes research that is tightly integrated with health system operations, with equal attention paid to measurable results and to the underlying methods of doing embedded research well. It is geared toward generating early evidence and actionable lessons that help health systems learn faster, implement improvements more reliably, and engage patients and stakeholders more meaningfully in the research and improvement cycle.Apply for PA 21 202
- The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "AHRQ/PCORI Learning Health System Small Grant Pilot Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226.
- This funding opportunity was created on 2021-03-11.
- Applicants must submit their applications by 2023-06-19. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs)
What is the AHRQ/PCORI Learning Health System Small Grant Pilot Program (PA 21 202)?
The AHRQ/PCORI Learning Health System Small Grant Pilot Program (Funding Opportunity Number PA 21 202) is a discretionary grant opportunity from the Agency for Healthcare Research and Quality (AHRQ), developed in partnership with the Patient-Centered Outcomes Research Institute (PCORI). It supports small, innovative pilot projects focused on patient-centered outcomes research conducted within Learning Health Systems (LHS).
Who is offering and partnering on this funding opportunity?
The program is offered by the Agency for Healthcare Research and Quality (AHRQ) and was developed in partnership with the Patient-Centered Outcomes Research Institute (PCORI).
What type of funding instrument is this?
This opportunity uses a grant as the funding instrument (Funding Instrument Type: Grant).
What is the main purpose of this pilot program?
The program funds pilot projects that embed patient-centered outcomes research into real-world health system care settings and operational workflows. The intent is to produce actionable evidence tied to decisions health systems are already making and to outcomes that matter to patients, clinicians, and other stakeholders.
What is meant by a "Learning Health System" (LHS) in this program?
In the context provided, a Learning Health System refers to a real-world care environment where research is embedded into routine operations and workflows, allowing the system to learn from practice and apply findings to improve decisions and outcomes.
What kinds of projects does this program prioritize?
The program prioritizes small, innovative pilot projects that are patient-centered, conducted within Learning Health Systems, and embedded directly into care settings and operational workflows.
What does "patient-centered outcomes research" mean in this opportunity?
Based on the description provided, patient-centered outcomes research focuses on outcomes that matter to patients (and also to clinicians and other stakeholders) and is closely tied to real-world decisions being made in health system settings.
What are the two main goals of the program?
The program is aimed at two connected goals: (1) supporting pilots that evaluate the outcomes of embedded research itself (for example, what changes or benefits occur when research is built into the health system environment), and (2) encouraging applicants to study the processes that make embedded research effective (such as partnerships, stakeholder engagement, implementation of findings, and practical facilitators and barriers).
What does it mean to evaluate the outcomes of "embedded research itself"?
It means applicants should examine what changes or benefits occur when research is built into the health system environment. Examples mentioned include improvements in patient outcomes, care processes, service delivery, quality measures, equity, or other priorities identified by the health system.
Is the program only interested in whether an intervention works?
No. The program is also interested in how embedded research is carried out and what makes it effective, including how teams partner with health system leaders, engage patients and stakeholders, implement findings, and address practical factors that help or hinder impact.
What kinds of process or "how it works" questions fit this program?
The opportunity highlights process topics such as how the research team partners with health system leaders, how patients and other stakeholders are engaged, how findings are implemented, and which practical factors enable or limit the impact of embedded research.
Where is the research expected to take place?
The research is expected to be conducted within real-world care settings and operational workflows of Learning Health Systems, and it is designed to be carried out domestically within U.S.-based organizational structures.
Who is eligible to apply?
Eligible applicants include a wide range of U.S.-based organizations and government entities, including state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities and Indian housing authorities; and nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in the nonprofit category). The opportunity also notes eligibility for faith-based or community-based organizations, regional organizations, U.S. territories or possessions, minority-serving institutions (including HBCUs, Hispanic-serving institutions, TCCUs, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISISs), and agencies of the federal government.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible, as long as they are not institutions of higher education in the nonprofit category (as described in the eligibility summary provided).
Are colleges and universities eligible?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible applicant types.
Are minority-serving institutions eligible to apply?
Yes. The eligibility summary specifically includes several categories of minority-serving institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Are tribal entities eligible?
Yes. The opportunity lists Native American tribal governments (federally recognized) and Native American tribal organizations (other than federally recognized tribal governments) as eligible.
Are faith-based or community-based organizations eligible?
Yes. The opportunity explicitly notes faith-based or community-based organizations among additional eligible groups.
Are U.S. territories eligible?
Yes. The eligibility summary includes U.S. territories or possessions.
Are federal government agencies eligible applicants?
Yes. Eligible applicant types include agencies of the federal government.
Can foreign (non-U.S.) organizations apply?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply.
Can a U.S. organization apply if part of the work is performed by a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible to apply, based on the restrictions described.
What is the activity category for this opportunity?
The opportunity is in the health activity category.
What CFDA number is associated with this program?
The program is described as consistent with the health-focused mission under CFDA 93.226.
When was this opportunity posted?
The posting was created on 2021-03-11.
What is the closing date listed in the summary information?
The original closing date listed is 2023-06-19.
How much funding is available per award (award ceiling)?
The summary information provided does not specify an award ceiling. Applicants would typically need to consult the full announcement for anticipated budget ranges and related details.
How many awards will be made?
The summary information provided does not specify the expected number of awards.
Does the summary specify the project period or award scale?
No. The summary notes that the award ceiling, expected number of awards, and other scale details are not specified, and that applicants typically need to consult the full announcement for budget ranges and project period information.
What kinds of outcomes might a pilot project measure?
Examples mentioned include improvements in patient outcomes, care processes, service delivery, quality measures, equity, or other priorities identified by the health system.
What is the overall focus of the program in plain terms?
It supports practical, real-world, patient-centered outcomes research that is tightly integrated with health system operations, with attention to both measurable results and the methods of doing embedded research effectively so that health systems can learn faster and implement improvements more reliably.
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